Human Neuronal disease models

discover our disease models

We generate human iPSC‑derived excitatory, inhibitory, dopaminergic, and motor neurons from patients, isogenic controls, and gene‑edited lines to enable robust analysis of disease mechanisms and treatment effects. All cell lines undergo extensive validation and a stringent quality‑control pipeline. By co‑culturing defined neuronal subtypes with other cell types as astrocytes or human muscle cells, we model neuronal activity and physiological processes in vitro with high fidelity, ensuring relevant and reproducible data for high‑content preclinical efficacy studies.

  • Neuro developmental disorders

    We offer an extensive library of synaptopathy and genetic epilepsy iPSC lines. Our excitatory and inhibitory iNeurons with functional assays deliver reliable, high‑quality preclinical efficacy insights.

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  • Motor Neuron diseases

    Our human motor neuron-muscle co-culture platform models neuromuscular junction (NMJ) formation and key ALS-associated phenotypes, enabling quantitative investigation of disease mechanisms and therapeutic responses in human-relevant systems.

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  • Neuro degenerative diseases

    Leveraging extensive expertise in Parkinson’s disease biology and human dopaminergic neuron systems, we provide validated human neuron models and functional assays that uncover neurodegenerative mechanisms and enable robust preclinical evaluation of therapeutic strategies.

    Read more »

  • Other Neurological disorders

    Our platform provides a comprehensive suite of tools for studying Central Nervous System (CNS) disorders. At Neurospector, we maintain an extensive collection of validated, patient-derived iPSCs and possess deep expertise in generating custom disease models using CRISPR/Cas9 genome editing.

    Read more »

  • Neuro developmental disorders

    We offer an extensive library of synaptopathy and genetic epilepsy iPSC lines. Our excitatory and inhibitory iNeurons with functional assays deliver reliable, high‑quality preclinical efficacy insights.

    Read more »

  • Motor Neuron diseases

    Our human motor neuron-muscle co-culture platform models neuromuscular junction (NMJ) formation and key ALS-associated phenotypes, enabling quantitative investigation of disease mechanisms and therapeutic responses in human-relevant systems.

    Read more »

  • Neuro degenerative diseases

    Leveraging extensive expertise in Parkinson’s disease biology and human dopaminergic neuron systems, we provide validated human neuron models and functional assays that uncover neurodegenerative mechanisms and enable robust preclinical evaluation of therapeutic strategies.

    Read more »

  • Other Neurological disorders

    Our platform provides a comprehensive suite of tools for studying Central Nervous System (CNS) disorders. At Neurospector, we maintain an extensive collection of validated, patient-derived iPSCs and possess deep expertise in generating custom disease models using CRISPR/Cas9 genome editing.

    Read more »

  • Neuro developmental disorders

    We offer an extensive library of synaptopathy and genetic epilepsy iPSC lines. Our excitatory and inhibitory iNeurons with functional assays deliver reliable, high‑quality preclinical efficacy insights.

    Read more »

  • Motor Neuron diseases

    Our human motor neuron-muscle co-culture platform models neuromuscular junction (NMJ) formation and key ALS-associated phenotypes, enabling quantitative investigation of disease mechanisms and therapeutic responses in human-relevant systems.

    Read more »

  • Neuro degenerative diseases

    Leveraging extensive expertise in Parkinson’s disease biology and human dopaminergic neuron systems, we provide validated human neuron models and functional assays that uncover neurodegenerative mechanisms and enable robust preclinical evaluation of therapeutic strategies.

    Read more »

  • Other Neurological disorders

    Our platform provides a comprehensive suite of tools for studying Central Nervous System (CNS) disorders. At Neurospector, we maintain an extensive collection of validated, patient-derived iPSCs and possess deep expertise in generating custom disease models using CRISPR/Cas9 genome editing.

    Read more »